Morton's neuroma belongs to the so-called pressure neuropathies, i.e. diseases manifested by impaired sensation in the area supplied by the compressed nerve. Morton's neuroma forms a pathological thickening of the common plantar nerve innervating the toes of the foot. This thickening is caused by mechanical irritation by misaligned metatarsal bones, transverse ligament of metatarsal heads or, less frequently, by the presence of a cystic nodule (ganglion).

Common symptoms of Morton's neuroma include a feeling of numbness and burning sensation in the second or third metatarsal spaces. Pain can radiate to the toes and is worsened when walking in narrow toe shoes or high heels. Initial diagnosis is facilitated by the Mulder test, which involves lateral compression of the foot at the level of the metatarsal heads. A sudden reduction in the space in which Morton's neuroma runs provokes pain and may cause a characteristic audible click. If Morton's neuroma is suspected, you should see an orthopedist who, in addition to clinical examination, will order imaging tests (ultrasound or magnetic resonance imaging).

Conservative treatment includes wearing shoes with wide toes and the use of orthopedic insoles that relieve the transverse arch of the foot. In the case of severe discomfort, a nerve block is performed. Surgical decompression of the nerve or complete excision of the neuroma is the best chance for a permanent cure.