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Celiac disease

Celiac disease - what is this disease?


Celiac disease is an autoimmune disease with a genetic background. It is caused by a malfunction of the immune system - as a result of which the body attacks its own tissues. This situation is caused by gluten, and more specifically its intolerance. Gluten is a grain protein found in wheat, rye, and barley. This means that it is present in most everyday products such as, among others. bread, pasta, cold cuts. For people with celiac disease, gluten is a real poison. It causes the disappearance of very important for humans - intestinal villi, which are responsible for obtaining nutrients from food. The direct causes of the impairment of the digestive system are deficiencies, malnutrition and malabsorption, which lead to very serious health consequences.

Make an appointment now - to the attending geneticist in our hospital

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Celiac disease - causes, symptoms


Celiac disease is primarily a genetic disease. It occurs in people who have the genotypes that determine its appearance: HLA DQ2.2 and / or HLA DQ2.5 or HLA DQ8. Numerous studies indicate that celiac disease may be associated with a hereditary burden.

Many people associate celiac disease primarily with gastric problems (diarrhea, abdominal pain, etc.). However, these kinds of symptoms appear in a relatively small number of patients. In fact, it is said that everyone has a different celiac disease. There may be anemia, fatigue, miscarriages, headaches, infertility or skin problems, for example.

What tests for celiac disease should be performed?

It is best to start the diagnosis of celiac disease with genetic tests recommended by the European Society of Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) as an effective method of diagnosing celiac disease.

TestDNA Laboratory testing for celiac disease includes the haplotypes: DQ2.2 (DQA1 * 02, DQB1 * 02), HLA DQ2.5 (DQA1 * 05, DQB1 * 02), HLA DQ8 (DQA1 * 03, DQB1 * 03).

In addition to the broadest scope of examination for celiac disease, the patient also receives recommendations from a doctor and a clinical dietitian for the result.

Genetic testing for celiac disease - why is it worth doing?


The lack of the DQ2.2, DQ2.5, DQ8 genes on the genetic test result means that we can complete the diagnosis of celiac disease in the first step, which saves us time and money. In addition, the gout test for celiac disease is a test whose result is not influenced by external factors such as the stage of the disease, age or a diet low in gluten. If the analysis shows the presence of at least one of the genes, the second step is to perform blood tests for antibodies. With the complete set of these results, you should see your doctor for diagnosis. Genetic testing for celiac disease is also very simple. The sample for celiac disease is a smear on the inside of the cheek. Moreover, this test is performed only once in a lifetime - there is no need to repeat it, because our genes do not change. Celiac disease is a hereditary disease, so information about whether we have genes responsible for the disease is also a diagnostic clue for our closest family members.

What is included in the DNA test for celiac disease:

A wide range of studied genes - DQ2.2, DQ2.5, DQ8 in the α and β subunit
test result in 7 business days
The test result also includes written medical and dietary recommendations, and with a positive result - additionally an exemplary gluten-free menu.
The test is covered by the sample guarantee
The price of a celiac disease test is PLN 297.

The patient can also perform the examination in express mode (result in 5 working days) - price PLN 377.

You can also carry out a package examination with lactose intolerance - the "Healthy Gut" package for PLN 494.

test for celiac disease - PLN 297

Lactose intolerance test - PLN 297

Healthy Intestines package PLN 494

 

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Szpital Dworska - Kraków

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