CONTACT: contact@dworska.pl | +48 12 352 25 25

Pain is usually one of the first symptoms of many medical conditions that prompt a patient to see a doctor. On the one hand, it is an alarm signal informing us that something is wrong with our body, on the other hand, it is important information for a doctor where to look for pathology and how to treat it. Regardless of the definition, it is certainly an unpleasant sensory and emotional experience related to the action of a damaging stimulus or a stimulus whose action threatens the occurrence of such damage.

Breakdown of pain

In practice, we can break down pain in many ways.

  1. By duration:

    1. acute <3 months

    2. chronic> 3 months

  2. By location:

    1. somatic pain - concerning receptors located more superficially, i.e. skin, subcutaneous tissue, musculoskeletal system - precise location of pain, corresponding to the location of pathology

    2. visceral pain - concerning receptors located inside the body cavities, i.e. the chest, abdominal cavity, pelvis - the location of pain is imprecise, diffuse, may radiate to distant parts of the body not directly related to the location of pathology - e.g. pain in the left upper limb and mandible, which may often be the only symptom of an acute infarction the heart muscle

  3. By reason:

    1. inflammatory - e.g. trauma, infection, autoimmune diseases

    2. neuropathic: peripheral and central - associated with damage to the nerve structures that can lead to pathological activation of the nervous system and chronic pain, despite the lack of a direct cause, e.g. diabetes-related neuropathy, post-herpetic neuropathy, ilio-inguinal nerve neuropathy after inguinal hernia surgery, etc.

    3.  nociceptor - as a result of direct stimulation of pain receptors, e.g. burns, wounds, direct pressure on nerves

    4. pain in cancer patients - usually of a mixed nature, both related to the direct stimulation of nociceptors, inflammation, but also damage to the central or peripheral nervous system as a result of the progressive neoplastic disease, but also as a result of treatment, e.g. toxicity of chemotherapy, radiotherapy or surgery

Summing up, pain does not arise only as a result of direct irritation of the sensory endings, but may be the result of a progressive underlying disease that leads to damage to various nervous structures that begin to incorrectly conduct sensory stimuli, or at the level of higher levels of the central nervous system, abnormal transduction, conduction, modulation (impulse processing) occurs nervous system) or the perception of a pain or sensation stimulus.

Pain management therapy

In the treatment of pain management, a multimodal multidisciplinary approach is important, requiring on the one hand cooperation between the surgeon, physiotherapist and the doctor dealing with pain management. Therefore, to achieve effective therapy and pain control, it is important to treat pain at many levels of its generation, transmission, modulation and perception pathways, which can be achieved by appropriately selected pharmacological treatment, but also by interventional treatment, usually including initially diagnostic blocks, but which may also have a therapeutic effect. In the case of positive responses, the patient may be qualified for a relapse to thermolesion or neurolysis treatments, which may bring many months' relief from ailments. All procedures and blockades performed under ultrasound control ensure greater precision and effectiveness as well as significantly reduce the risk of any complications and complications associated with these procedures. The final choice of therapy and treatment plan should be individually selected for the patient and his expectations, taking into account the coexisting diseases, medications taken as well as the economic and social situation of the patient.

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Współpraca z testDNA – nowe badania genetyczne w Szpitalu Dworska

testDNA LOGO

Szpital Dworska rozpoczął współpracę z testDNA Laboratorium Sp. z o.o. – wiodącym laboratorium genetycznym na rynku. Dzięki temu w naszej placówce mogą Państwo wykonać nowe badania DNA, m.in. testy na ojcostwo (w ciąży i po narodzinach dziecka), badania w kierunku nietolerancji pokarmowych czy test NOVA (nowoczesne badanie dla dzieci).

logo nova

Kompleksowa oferta badań DNA w szpitalu Dworska

testDNA Laboatorium Sp. z o.o. realizuje zarówno testy związane z ojcostwem i pokrewieństwem, jak i badania z zakresu diagnostyki medycznej. W szpitalu Dworska mogą więc Państwo wykonać przede wszystkim:

  • testy na ojcostwo – w najszerszym zakresie na rynku (nawet 34 markery DNA), z dowolnych próbek (np. wymazy z policzka, maszynka do golenia, smoczek);
  • testy na ojcostwo w ciąży – możliwe już od 8. tygodnia ciąży (najwcześniej dostępne badanie tego typu na świecie);
  • testy na pokrewieństwo – pozwalające sprawdzić więzy krwi, np. dziadków i wnuka czy rodzeństwa;
  • test NOVA (nowoczesne badania dla noworodków i dzieci) – sprawdzające aż 12 tysięcy zmian w genach, dzięki czemu możliwe jest wyprzedzenie rozwoju niebezpiecznych chorób wrodzonych;
  • badania w kierunku nietolerancji pokarmowych –celiakii i nietolerancji laktozy;
  • badanie w kierunku trombofilii wrodzonej – wskazujące tendencję do zmian zakrzepowych;
  • badania materiału poronnego – określające płeć materiału poronnego (co jest niezbędne do skorzystania z praw po poronieniu) i pozwalające sprawdzić, czy do straty przyczyniła się jedna z najczęściej występujących chorób genetycznych.
  •  profilaktyczne testy przesiewowe dla noworodków i dzieci do lat 5 (test NOVA, test NOVA+)
  •  badania dla dzieci z objawami autyzmu (badanie WES, mikromacierz, badanie FRAX, panel NGS 224 genów związanych z autyzmem)
  •  badania dla dzieci z padaczką (badanie WES, panel NGS 132 genów związanych z padaczką)
  •  badania dla dzieci, które często chorują (badanie WES w kierunku wrodzonych niedoborów odporności)
  •  diagnostyka genetyczna chorób jednogewych (panele NGS wybranych genów)

TestDNA Laboratorium Sp. z o.o. – pewne i wiarygodne badania

testDNA Laboratorium Sp. z o.o. posiada akredytację PCA – będącą gwarancją pewności, bezstronności i niezależności w działaniu, a także oficjalnym potwierdzeniem kompetencji laboratorium. Regularnie bierze ponadto udział w kontrolach zewnętrznych i uzyskuje certyfikaty, m.in. Gednap, ISFG i UK NEQAS.

Wiarygodność wyników zapewniają także stosowane wysokiej jakości odczynniki, nowoczesny sprzęt i oprogramowanie. Marka testDNA działa na rynku już 16 lat.

Umów wizytę teraz - do lekarza, który zajmuje się kwalifikacją do badań genetycznych w naszym szpitalu

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Preventive examinations in children and newborns - how can genetics help?

Prevention in children - it can save health and life

Preventive examinations are very important - thanks to them, you can get valuable information about your child's health at an early stage - which means a good chance of preventing complications. This is also the case with the risk of developing a congenital disease. What Are Congenital Diseases? These are diseases that are written in genes. A child is born with a damaged gene, but it does not always make itself felt immediately after birth. Unfortunately - many congenital diseases can develop secretly for many years - and be asymptomatic for a long time. They can also cause symptoms that will be very confusing for parents and doctors - for example, diarrhea, drowsiness, frequent infections, muscle tension disorders, and many other symptoms that can be interpreted as normal childhood ailments that will 'pass by themselves'. Unfortunately - if they are caused by a congenital disease - they 'will not go away', on the contrary - they will intensify. Undiagnosed and untreated congenital diseases can, unfortunately, lead to tragic consequences - permanent intellectual delay (including symptoms from the autism spectrum), physical development disorders, and even the risk of cancer and severe infections.

Make an appointment now - to the attending geneticist in our hospital

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Preventive examinations in children and newborns - stay ahead of the symptoms of a congenital disease


Rapid diagnosis of congenital disease - right after birth or at the stage of the first symptoms, gives doctors and parents a chance to stop its progression! Knowing early about the risk of congenital disease can help you take quick steps and initiate appropriate treatment. It may, for example, involve the introduction of an individual diet (for metabolic diseases) or targeted, reimbursed treatment (e.g. for congenital immunodeficiencies). Thanks to this, the child has a chance for a normal life and development. Knowing about a congenital disease also means information in the context of immunization. In the course of many congenital diseases, an individual child's immunization schedule is required.

Prevention in children - bet on genetics!


You can already perform very modern tests that will check hundreds of your child's genes in one analysis. Thanks to this, you will gain important knowledge whether the child is at risk of developing a congenital disease, and therefore - whether it requires an individual approach to diet, immunization or whether it requires targeted life-saving treatment. Genetic testing can be performed as early as on day 2 of a child's life, thanks to which the above knowledge can be obtained very early.

Genetic preventive examinations in the testDNA Laboratory


We offer two packages of genetic preventive screening tests for newborns and children up to 5 years of age. In one analysis, they determine the risk of contracting several dozen congenital diseases. The sample for both tests can be taken already on the second day of life. As the sample is a cheek swab, its collection is painless and stress-free, and easy to perform (parents can take the sample even on their own.

NOVA test - a modern genetic test for newborns and children up to 5 years of age to verify the risk of developing 87 congenital diseases:

68 metabolic diseases
12 congenital immunodeficiencies
2 other immune diseases,
5 other common diseases (including cystic fibrosis, Dravet syndrome)

Additionally, the study includes:

drug sensitivity panel (32 medicinal substances),
test sample: cheek swab

Price: PLN 3 887

The waiting time for the result: 5-6 weeks

The NOVA + test is a modern genetic test for newborns and children up to 5 years of age, verifying the risk of contracting 91 congenital diseases.

68 metabolic diseases
12 congenital immunodeficiencies
2 other immune diseases,
7 other common diseases (including cystic fibrosis, Dravet syndrome, haemochromatosis, hereditary thrombophilia),
2 food intolerances: lactose and gluten (celiac disease).
Additionally, the study includes:

drug sensitivity panel (32 medicinal substances),
test sample: cheek swab

Price: 4 887 PLN

The waiting time for the result: 5-6 weeks

WES test - the most extensive genetic test on the market

WES (Whole Exome Sequencing) research is the most comprehensive and modern genetic research based on NGS (Next Generation Sequencing) technology. The WES study sequences the entire human exome, i.e. all genes known at the moment (approx. 23,000 - gene coding sequences are analyzed) that may lead to the development of symptoms of genetic diseases. The WES test can be performed in both adults and children and is completely safe.

Thanks to the WES test, a wide differential diagnosis is possible - checking in one analysis (from one patient sample) hundreds of genetic causes of disturbing symptoms occurring in the patient. This means a significant shortening of the diagnostic path and avoiding the so-called a diagnostic odyssey - when the suspicions of further diseases are excluded in subsequent tests and finding the true cause of the disease takes years and carries high costs. And worst of all, it postpones the time of diagnosis and possible targeted treatment.

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When is the WES test particularly advisable?
- in the case of symptoms from the autism spectrum and intellectual development disorders,

- in the case of epilepsy and other neurological disorders of unknown origin,

- in the case of immunodeficiency and frequent infections (for congenital immunodeficiencies),

- in the case of orthopedic problems (dysplasia, rickets, osteogenesis imperfecta and others)

- in the case of dysmorphic features - atypical facial features,

- in the case of muscular dystrophies,

- in the case of hematological and cardiological disorders of unknown cause,

- in the case of the risk of oncological diseases,

- in the case of lung diseases of unknown origin,

- when a metabolic disease is suspected.

Importantly, the WES test allows not only to check the genetic causes of the existing symptoms, but also to obtain other relevant information about health (the risk of developing diseases that have not yet produced symptoms). The WES test also shows the carrier status, which is very important in family planning and disease risk assessment in the offspring and the patient's family.

WES test in the testDNA Laboratory


the scope of the study includes the analysis of the human exome and CNV changes (microdeletions and microduplications within the examined exome. This range is similar to the study of microarrays - molecular karyotype),
test sample: blood (we arrange for you to collect a sample for testing at the facility)
waiting time for the result: up to 10 weeks
if the patient agrees, he or she may obtain information about the risk of developing other genetic diseases unrelated to the current symptoms or family genetic burden,
once a gene analysis has been performed, it is possible to return to the future (without the need to re-sample). Thanks to this, it is possible to check if the state of medical knowledge has not changed and if no new mutations have been found that may cause disturbing symptoms,
price: 5 497 PLN 

WES test - what will it not check? 


It should be remembered that, like any genetic test, also the WES test has its limitations. The analyzed changes in the genetic material include point mutations in genes and CNV changes (so-called copy number variants). They are the cause of most genetic diseases. However, the WES test does not report the scope of the standard karyotype test, nor the so-called dynamic mutations in genes. This is due to technological limitations. The attending physician (genetics) is responsible for the final interpretation of the result and the influence of the detected mutation on the clinical symptoms present in the patient.

Congenital thrombophilia - what is it?


Congenital thrombophilia is the tendency to clot in our genes. Many patients are unaware that thrombophilia can affect him because it does not show any visible symptoms. The mutations / changes that cause it are most often a factor V Leiden mutation, a mutation in the prothrombin gene. The following are also frequently analyzed: PAI-1 / SERPINE1, V R2 and MTHFR (C677T and A1298C), which also, but in a milder way, increase the risk of thromboembolic diseases.

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Congenital thrombophilia test - when is it worth doing?
If:

you are after a thrombotic event or pulmonary embolism,
thromboembolism in the immediate family or the above-mentioned mutations,
you miscarried 2 or more times
you use hormonal contraception (according to the Recommendation of the Polish Gynecological Society, women with factor V Leiden mutations and the prothrombin gene should absolutely not use this form of contraception)

Why is it worth testing for congenital thrombophilia?


First of all, knowing if you have mutations associated with an increased risk of blood clots, you can implement appropriate preventive measures that will not further promote their formation, e.g. use an appropriate lifestyle. Additionally, if you have a burdened history (e.g. you are after a thromboembolic event), your doctor may recommend appropriate treatment for you, e.g. before trying for another pregnancy or a long flight - this way you can reduce the negative effects of the mutation.

How can I be tested for hereditary thrombophilia?


The sample for congenital thrombophilia is a smear on the inside of the cheek. You do not need to fast for the test. Importantly, this test is done only once in a lifetime - there is no need to repeat it because our genes do not change. It is worth knowing that congenital thrombophilia is hereditary, so information about whether we have any mutations is also a diagnostic clue for our closest family members. The result should always be consulted with a geneticist who will tell you what it means for the patient, and whether it is worthwhile to start appropriate treatment.

Price of the study for thrombophilia and implementation time


The study includes:

factor V Leiden mutation
mutation of the prothrombin gene
MTHFR (C677T and A1298C)
PAI-1 / SERPINE1
V R2
The delivery time with the package is 7-10 business days. The price of this package is PLN 347. If the patient wants the result in express mode (4-5 business days) and wants to consult a geneticist, he or she can choose the Premium Package for PLN 457.

Paternity tests are the surest way to check if the tested man is the biological father of the child being tested. The result allows not only to regain peace and breathe a sigh of relief, but also to solve the legal situation of the family. The test can be performed on any sample - not only a cheek swab, but also a nipple, cigarette butt or razor. What is the paternity test, and what else should I know?

Make an appointment now - to the attending geneticist in our hospital

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What is the paternity test?


The paternity test involves taking DNA samples from test subjects, determining genetic profiles, and then comparing them. Genetic profiles are commonly referred to as "genetic fingerprints" because each of us (except for identical twins) has a unique profile. The comparison of the profiles makes it possible to unequivocally determine whether the examined child comes from the examined father.

DNA tests clearly confirm or exclude paternity. To produce a certain result, the participation of the father and the child is sufficient.

What samples are suitable for the paternity test?
Any sample is used for paternity testing, e.g.

cheek swabs,
nipple,
a razor,
cigarette butt,
mug, glass, glass,
cutlery,
soda can,
a toothbrush,
a handkerchief with a runny nose,
a patch with a blood stain,
meter strip,
lollipop stick.

Importantly, each sample is equally certain, so it is best to pass the one that is easiest to collect for testing. The DNA fragments analyzed in the paternity test are unchanged regardless of the type of sample.

testDNA Laboratorium Sp. z o.o. has experience in the analysis of various types of materials, does not divide samples into "better" and "worse". Each sample is additionally covered by the warranty - if for some reason it is not suitable for testing (e.g. DNA degradation), another one can be provided free of charge.

When is it worth taking a paternity test?


The paternity test is a test that allows you to resolve many family issues, dispel doubts and regain peace. In fact, there are as many Patient Stories as paternity tests. But what are the most common reasons for taking paternity tests? The paternity test is worth doing, among others in a situation where:

doubts appeared - related to, for example, suspicion of betrayal, lack of similarity, gossip in the family or incompatible blood type;
you want to check whether the maintenance is paid correctly;
you need evidence in a court case - e.g. for denial or paternity;
you need proof for the prosecutor's office - when the time limit for the father to deny paternity has expired, only the prosecutor who needs proof that it is justified may file a claim;
you want to make sure before paternity is recognized in the Civil Registry Office;
you suspect a baby change in hospital.

Is the paternity test result certain?

Yes - the result of the paternity test is reliable if the test is performed in a reliable laboratory. The most important factors for a certainty of the result are:

analysis of up to 34 DNA markers - in testDNA Laboratorium Sp. z o.o. each tested person has 24 to 34 DNA markers, which guarantees a certain result even with the participation of only the father and the child;
results issued in accordance with the recommendations of the Polish Society of Forensic Medicine and Criminology - i.e. confirmation of paternity with a probability of over 99.9999% and exclusion of 100%;
PCA accreditation and certificates - courts and the police may commission tests only in accredited laboratories, as this is a guarantee of competence and independence in action; certificates are also important, incl. GEDNAP and ISFG;
high-quality reagents - i.e. those with validation that are checked from every angle;
rigorous safety procedures in place - e.g. performing the test twice, from two samples, by two different teams in the case of a result that excludes paternity.

How much does the paternity test cost and what is the deadline for completion?


The paternity test costs PLN 1247. This is the final price which includes:

analysis of 24 DNA markers (with free extension to 34 DNA markers if necessary),
sampling at the facility or self-collection at home,
analysis in a laboratory with PCA accreditation,
online access to the result and / or sending the result by post,
testing of any samples (with guarantee until effect).
The test result is available within 3-5 working days from the time the samples arrive at the laboratory (cheek swabs from all persons) or up to 10 working days (minimum discrete sample for one person).

If you want to speed up the result, you can perform the test in the express mode (result up to 48 hours), the price of which is PLN 1647.

At the price of PLN 1447, an option with the analysis of 34 markers as standard is also available.

Kontakt

ul. Dworska 1B, 30-314 Kraków
rejestracja@dworska.pl


Szpital Dworska - Kraków

Opening hours

Monday:
7:30 - 20:30
Tuesday:
7:30 - 20:30
Wednesday:
7:30 - 20:30
Thursday:
7:30 - 20:30
Friday:
7:30 - 20:30
Saturday:
7:30 - 14:00
Sunday:
Closed
lokalizacja parkingu

Parking next to Dworska Hospital - entrance from the Bułhaka street